http://www.thecherrycreeknews.com/what-does-the-research-show-about-medical-marijuana-and-how-to-make-weed-brownies-safely/
We have no political position on marijuana legalization. We study the marijuana plant, likewise referred to as marijuana, and its related chemical substances. In spite of claims that cannabis or its extracts eliminate all sorts of maladies, the research has actually been sporadic and the outcomes blended. At the minute, we just do not know adequate about cannabis or its components to evaluate how reliable it is as a medicine.
What does the offered research study suggest about medical cannabis, and why do we understand so little about it?
The jury is still out on marijuana's medical advantages. Thomas Hawk/Flickr, CC BY-NC
Exactly what are scientists studying?
While some scientists are investigating smoked or vaporized marijuana most are looking at specific marijuana compounds, called cannabinoids.
From a research study standpoint, marijuana is considered a "dirty" drug due to the fact that it includes numerous compounds with badly understood effects. That's why scientists tend to concentrate on just one cannabinoid at a time. Just 2 plant-based cannabinoids, THC and cannabidiol, have been studied thoroughly, but there might be others with medical advantages that we do not understand about.
THC is the primary active element of cannabis. It activates cannabinoid receptors in the brain, causing the "high" associated with marijuana, as well as in the liver, and other parts of the body.
Cannabidiol (likewise called CBD), on the other hand, doesn't engage with cannabinoid receptors. It does not trigger a high. Seventeen states have actually passed laws enabling access to CBD for individuals with specific medical conditions.
Our bodies likewise produce cannabinoids, called endocannabinoids. Researchers are producing new drugs that modify their function, to much better understand how cannabinoid receptors work. The objective of these research studies is to discover treatments that can use the body's own cannabinoids to deal with conditions such as chronic pain and epilepsy, rather of using marijuana itself.
Marijuana is promoted as a treatment for many medical conditions. We'll have a look at two, chronic discomfort and epilepsy, to highlight exactly what we in fact learn about its medical benefits.
Is it a chronic pain treatment?
Research study recommends that some people with persistent discomfort self-medicate with cannabis. However, there is limited human research study on whether marijuana or cannabinoids effectively lower chronic discomfort.
Research in people suggest that particular conditions, such as chronic discomfort caused by nerve injury, may react to smoked or vaporized cannabis, in addition to an FDA-approved THC drug. But, the majority of these research studies count on subjective self-reported pain rankings, a considerable restriction. Just a few controlled clinical trials have been run, so we can't yet conclude whether cannabis is an effective pain treatment.
An alternative research technique focuses on drug mix therapies, where an experimental cannabinoid drug is integrated with an existing drug. For instance, a recent research study in mice integrated a low dose of a THC-like drug with an aspirin-like drug. The mix blocked nerve-related discomfort much better than either drug alone.
In theory, the advantage to mix drug treatments is that less of each drug is required, and negative effects are lowered. In addition, some people might respond much better to one drug ingredient than the other, so the drug mix may work for more people. Comparable research studies have actually not yet been run in people.
Well-designed epilepsy studies are badly needed
In spite of some sensational news stories and prevalent speculation on the internet, using marijuana to lower epileptic seizures is supported more by research in rodents than in people.
In people the evidence is much less clear. There are lots of anecdotes and surveys about the positive results of marijuana flowers or extracts for treating epilepsy. These aren't the exact same thing as well-controlled scientific trials, which can inform us which types of seizure, if any, react positively to cannabinoids and provide us more powerful forecasts about how the majority of people respond.
While CBD has actually acquired interest as a possible treatment for seizures in people, the physiological link in between the 2 is unidentified. Just like chronic discomfort, the few clinical studies have actually been done consisted of few patients. Research studies of larger groups of people can inform us whether just some clients react favorably to CBD.
We likewise have to understand more about the cannabinoid receptors in the brain and body, what systems they control, and how they could be influenced by CBD. For circumstances, CBD may interact with anti-epileptic drugs in methods we are still discovering about. It might likewise have various results in an establishing brain than in an adult brain. Caution is especially advised when seeking to medicate children with CBD or cannabis items.
We study the marijuana plant, also known as cannabis, and its associated chemical substances. From a research viewpoint, cannabis is thought about a "filthy" drug since it consists of hundreds of compounds with poorly understood effects. It activates cannabinoid receptors in the brain, causing the "high" associated with cannabis, as well as in the liver, and other parts of the body. The objective of these research studies is to find treatments that can utilize the body's own cannabinoids to treat conditions such as chronic discomfort and epilepsy, rather of using marijuana itself.
Research in people recommend that specific conditions, such as persistent discomfort caused by nerve injury, may respond to smoked or vaporized marijuana, as well as an FDA-approved THC drug.
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